What is a possible consequence of untreated diabetes mellitus?

In the context of untreated diabetes mellitus, one of the serious consequences is the development of kidney failure and cardiovascular disease. Chronic high blood glucose levels associated with unmanaged diabetes can lead to a variety of complications over time.

The kidneys may be particularly affected, as diabetes can cause damage to the small blood vessels within the kidneys, a condition known as diabetic nephropathy. This damage impairs the kidneys' ability to filter waste from the blood, ultimately leading to kidney failure. Moreover, diabetes increases the risk of cardiovascular diseases due to its negative impact on blood vessel integrity and function, leading to conditions such as hypertension, atherosclerosis, and heart attacks.

In contrast, severe allergic reactions, asthma exacerbation, and acid-base imbalance are generally not direct consequences of untreated diabetes. While individuals with diabetes may experience other health issues, the link between untreated diabetes and the development of kidney failure and cardiovascular problems is well-established and significant.